Exemestane is an aromatase inhibitor used in bodybuilding to suppress the estrogenic side effects of steroids. It is also known as Aromasin, which was patented by Upjohn, the company that made it. The anti-estrogen first appeared on the US market in the early 2000s, immediately after it was approved for sale.
Like other representatives of this class of antiestrogens, exemestane is actively used in the treatment of breast cancer in menopausal women. However, the drug is no less popular in sports, as it can effectively suppress the estrogenic side effects of AAS. The mechanism of action is similar to that of the more well-known aromatase inhibitors letrozole and anastrozole. However, unlike them, athletes often use exemestane in bodybuilding after a steroid cycle.
Beneficial effects and properties of Exemestane
As mentioned above, Exemestane is able to effectively block the aromatase enzyme responsible for converting testosterone into female hormones. This lowers the estrogen concentration in the blood. Thanks to this, the drug is effective in the fight against breast cancer, since its development is directly related to an increase in estrogen levels. The same fact made Exemestane popular among athletes who are actively using steroids.
Many AAS have the ability to aromatize and this leads to the development of certain side effects such as fluid retention in the body and gynecomastia. The most serious negative effect among them is considered the other. However, with active fluid retention, blood pressure can rise significantly.
Numerous studies have shown that an increase in progesterone levels leads to the development of gynecomastia. By using exemestane in bodybuilding during a steroid cycle, the athlete can eliminate the risk of estrogenic side effects. Research has shown that Aromasin can reduce blood levels of estradiol by up to 85 percent of baseline.
That’s not the only positive property of the fabric that has made it popular with builders. The fact is that taking exemestane in bodybuilding after a course of steroids can accelerate the secretion of endogenous male hormone.
Some athletes do just that by including this aromatase inhibitor in their PCT. It should be recognized that letrozole and anastrozole also have a similar effect. They can send a signal to the pituitary gland about the need to start producing hormones of the gonadotropic group – luteinizing and follicle-stimulating.
But exemestane has some advantages over these drugs:
- It has low androgenic activity.
- Accelerates insulin-like growth factor secretion.
No other member of the aromatase inhibitor class has these properties. By using exemestane in bodybuilding after a steroid cycle, an athlete can not only quickly restore the processes of testosterone synthesis, but by increasing the concentration of insulin-like growth factor, it shifts the balance between anabolism and catabolism in the direction of the former.
Some builders are sure that this has a positive effect on body recovery, as it minimizes the rollback effect and protects muscle tissue from destruction. However, when you look at the immediate results of using Exemestane in bodybuilding after a cycle of steroids, it becomes clear that this is not desirable. Summarizing the conversation about the positive effects of the drug, we highlight the main ones:
- An excellent tool for the prevention of gynecomastia.
- Effectively suppresses the level of female hormones.
- Promotes the growth of the anabolic background.
- Improves muscle relief.
- It is a good remedy for preventing high blood pressure.
- Reduces the negative effects of estrogens on the work of the pituitary gland.
Instructions on how to use exemestane in bodybuilding
The recommended dose of the drug is in the range of 12.5 to 25 milligrams and should be taken every other day. In most cases, however, it is sufficient for athletes to take exemestane in an amount of 12.5 milligrams up to three times a week.
If the maximum allowable dose is used, then the duration of such a course of eczema should not be long. It’s only worth using 25 milligrams if your cholesterol is out of whack and sticking to the minimum dose in other situations. Exemestane is also sometimes used in professional sports one to two weeks before the start of a tournament, which can improve muscle relaxation.